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Can we predict who will develop bipolar disorder?

Professor Philip Mitchell

What factors determine which children or siblings of those with bipolar disorder will develop this condition and who will be resilient to this? Elucidation of such factors would enable development of rational preventive or early intervention programs.

The prospective longitudinal Bipolar Kids and Sibs Study has enrolled 150 children and young adults aged between 12 and 30 who are at risk of (BD) because they have a first degree relative with the disorder. Ten per cent of these individuals can be expected to go on to develop BD.

12th Biennial Australasian Schizophrenia Conference
13-14 May 2013 Melbourne, Australia.
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Philip Mitchell
Philip Mitchell
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Professor Philip Mitchell

Philip Mitchell is Professor and Head of the School of Psychiatry at the University of New South Wales; Convenor of Brain Sciences UNSW; Chair of the NSW Mental Health Priority Taskforce; Consultant Psychiatrist, Black Dog Institute, Sydney; Guest Professor, Shanghai Jaitong University; and Board Member of the Anika Foundation. His research and clinical interests are in bipolar disorder and depression, with a particular focus on the molecular genetics of bipolar disorder, transcranial magnetic stimulation (TMS) for depression, and the pharmacological and psychological treatment of bipolar disorder and depression. 

Professor Mitchell has published (in conjunction with colleagues) over 370 papers or chapters on these topics and is a member of an NHMRC-funded Program Grant on depression and bipolar disorder. He is an assistant editor of the Australian and New Zealand Journal of Psychiatry and Therapeutic Advances in Chronic Disease and Neuropsychiatry. He also serves on the editorial boards of Psychiatric Genetics, CNS Drugs, CNS Spectrums, Therapeutic Advances in Psychopharmacology, Current Therapeutic Research and Medicine Today. In 2002 Professor Mitchell was awarded the Senior Research Award of the Royal Australian and New Zealand College of Psychiatrists.

In 2004, he received the Founders Medal of the Australasian Society for Psychiatry Research. In 2009 he was appointed a Scientia Professor, UNSW (2009-2014), for his international eminence in research. Professor Mitchell also serves on the NSW Health Care Advisory Council. He was appointed as a Member of the Order of Australia in the 2010 Australia Day Honours List for service to medical education, particularly in the field of psychiatry, as an academic, researcher and practitioner, through contributions to the understanding, treatment and prevention of mental illness.

Co-authors: G Roberts, M Green, M Breakspear, A Frankland, P Lau, C Joslyn, F Levy, R Lenroot, A English, B Radlinska, J Fullerton, P Schofield
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