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Current Medical Treatment of Premature Ejaculation

Dr. Chris McMahon

Over the past 20-30 years, the Premature Ejaculation (PE) treatment paradigm, previously limited to behavioural psychotherapy, has expanded to include drug treatment. Animal and human sexual psychopharmacological studies have demonstrated that serotonin and 5-HT receptors are involved in ejaculation and confirm a role for SSRIs in the treatment of PE. Multiple well-controlled evidence-based studies have demonstrated the efficacy and safety of SSRIs in delaying ejaculation, confirming their role as first-line agents for the medical treatment of lifelong and acquired PE. Daily dosing of SSRIs is associated with superior fold increases in IELT compared to on-demand SSRIs.

Conflict of Interest: None disclosed
Financial Support/Funding: Supported by an unrestricted educational grant by Janssen-Cilag.
Recorded: Australian Center for Sexual Health, Sydney, Australia, June 2009

Chris McMahon
Chris McMahon
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Dr. Chris McMahon

Dr Chris G McMahon is a Sexual Health Physician and Fellow of the Royal Australian College of Physician’s Chapter of Sexual Medicine. He is  the Director of the Australian Centre for Sexual Health in Sydney. Dr McMahon is a committee chairman for the WHO Second and Third International Consultation on Erectile and Sexual Dysfunction and a chairman of the International Society of Sexual Medicine (ISSM) medical and research standards committee. He is an Associate Editor of the Journal of Sexual Medicine, an associate section editor of the British Journal of Urology and a member of the editorial board of the International Journal of Sexual Health, Current Sexual Health Reports and the Journal of Men’s Health. He has been invited to lecture on sexual medicine worldwide and has published extensively on sexual health. He has published over 60 original research and invited review articles in peer reviewed international medical journals, and 13 books or book chapters.

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Australia Society for Psychological MedicineANZAPWorld Council for PyschtherapyPACFABrisbane Institute of Strength Base PraticeISHHR - International Society for Health and Human RightWAS - World Association for Sexual HealthMissing of HopeAABCAPSTARTTSANSA