Psychevisual.com, Jury Kropotov, Event Related Potentials, Schizophrenia, Diagnosis, Treatment, ERP, ADHD, P3b, tDCS, ICA

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Event Related Potentials in Schizophrenia: Implications for Diagnosis and Treatment.
Prof. Jury Kropotov

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The review of research of event related potentials (ERPs) shows that the most common scientific observation is decrease of the P3b wave both in ADHD and schizophrenia. This observation appears to reflect a common dysfunction in ADHD and schizophrenia in the parietal attention system. Dopamine hypotheses of ADHD and schizophrenia will be discussed. The hypotheses imply involvement of different aspects of information processing within the basal ganglia thalamocortical circuits. A recently emerged independent component analysis (ICA) provides a powerful tool for decomposing ERPs into components of different functional meanings. The paper will describe results of application of Independent Component Analysis (ICA) for decomposing a collection of ERPs into independent components associated with different psychological operations (such processing in dorsal and ventral visual streams, orienting response, engagement, motor suppression and conflict monitoring operations). 1000 healthy subjects, 1000 patients with ADHD and 100 patients with schizophrenia participated in this multi-center European study including laboratories from Switzerland (A. Mueller et al.), Norway (S.Hollup et al.), Macedonia (N. Pop-Jordanova et al), and Russia (Kropotov et al). The results of application of the ERP ICA for diagnosis (discrimination) ADHD and schizophrenia from healthy subjects will be presented. In the final part of the paper a methodology for constructing protocols of neurofeedback and tDCS on the basis of comparison the individual ERP parameters with the normative data will be presented. Recently emerged methods of neurotherapy such as sLORETA-based, ERP-based neurofeedback and tDCS will be also introduced in relation to neuromodulation in ADHD and schizophrenia.

Applied Neuroscience Society of Australasia. Annual Conference
Cognitive Enhancement, Neuromodulation and Neurodiagnostics.
Sydney Australia . August 12-14 2011
Visit ANSA at http://www.appliedneuroscience.org.au

Jury Kropotov

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TITLE	SPEAKER	DURATION
Event Related Potentials in Schizophrenia: Implications for Diagnosis and Treatment.	Jury Kropotov	28'30"
Event Related Potentials in Schizophrenia: Implications for Diagnosis and Treatment.	Jury Kropotov
Event Related Potentials in Schizophrenia: Implications for Diagnosis and Treatment.	Jury Kropotov

Prof. Jury Kropotov

Director of laboratory for neurobiology of action programming at Institute of the Human Brain of the Russian Academy of Sciences, St.-Petersburg, Russia and Professor II at the Institute of Psychology at Norwegian University for Science and Technology in Trondheim, Norway.

Yuri Kropotov graduated from the department of physics (major in quantum mechanics) at St.-Petersburg State University in 1972. In 1975 he defended his PhD thesis on “Slow processes in the human brain” at the Institute for Experimental Medicine.

In 1985 for his research in the field of human physiology he was awarded the State Prize of the USSR – the highest award in the former Soviet Union. He was the first to show that the basal ganglia thalamo-cortical circuits of the human brain are involved in cognitive and affective functions.

In 1986-1992 he developed a mathematical model of the cortex – the canonical cortical module – that was able to explain most of the properties of neurons in the visual cortex. In 1990s he started the research in the field of quantitative EEG and evoked potentials in normal subjects, in ADHD population and in neurological patients to whom intracranial electrodes were implanted for diagnosis and therapy.

In 1998 he began using neurofeedback and transcranial Direct Current Stimulation for treatment ADHD and some other brain dysfunctions. For his research he was awarded the Medal of Honor of Russian Federation, the Diploma of the USSR Academy of Sciences for the Highest Achievement (Discovery) in science.

He published more than 180 papers and 7 books. For many years he served as an editor of the journal “Human Physiology” of Russian Academy of Sciences. He is ex-president of the European Chapter of international Society for Neuronal Regulation (ISNR) and an editor of the journal “Neurotherapy”.

The Academic Press just published his new book: Quantitative EEG, Event-Related Potentials and Neurotherapy which is quickly becoming the must have reference and textbook for QEEG students and practitioners.